The GC-IGF1 axis-mediated testicular dysplasia caused by prenatal caffeine exposure
نویسندگان
چکیده
منابع مشابه
Prenatal Caffeine Exposure Impairs Pregnancy in Rats
Background In recent years, concerns have been raised about human reproductive disorders. Caffeine consumption is increasing by the world’s population and there is a relationship between caffeine intake and adverse reproductive outcomes. The aim of this study was to evaluate the effects of caffeine on implantation sites, number of live births, birth weight, crown-rump length (CRL) and abnormali...
متن کاملprenatal caffeine exposure impairs pregnancy in rats
background: in recent years, concerns have been raised about human reproductive disorders. caffeine consumption is increasing by the world’s population and there is a relationship between caffeine intake and adverse reproductive outcomes. the aim of this study was to evaluate the effects of caffeine on implantation sites, number of live births, birth weight, crown-rump length (crl) and abnormal...
متن کاملPrenatal Caffeine Exposure Impairs Pregnancy in Rats
BACKGROUND In recent years, concerns have been raised about human reproductive disorders. Caffeine consumption is increasing by the world's population and there is a relationship between caffeine intake and adverse reproductive outcomes. The aim of this study was to evaluate the effects of caffeine on implantation sites, number of live births, birth weight, crown-rump length (CRL) and abnormali...
متن کاملSpace radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine
Travel into outer space is fraught with risk of exposure to energetic heavy ion radiation such as (56)Fe ions, which due to its high linear energy transfer (high-LET) characteristics deposits higher energy per unit volume of tissue traversed and thus more damaging to cells relative to low-LET radiation such as γ rays. However, estimates of human health risk from energetic heavy ion exposure are...
متن کاملThe GH-IGF1 axis and longevity. The paradigm of IGF1 deficiency.
Primary or secondary IGF1 deficiency has been implicated in shortening of lifespan. This paper reviews available data on the influence of IGF1 deficiency on lifespan and longevity in animals and man. It has been shown that inactivation of the IGF1 gene or of the GH receptor in both invertebrates (C-elegans, flies-Drosphila) and rodents (mice and rats), leading to IGF1 deficiency, prolong life, ...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 2019
ISSN: 0022-0795,1479-6805
DOI: 10.1530/joe-18-0684